IV Acetadote Dosage Calculator

Use the Acetadote dosage calculator to calculate the accurate dose of Acetadote for your patients.


Enter your patient's weight below and click "Calculate."

Enter patient weight: Pounds Kilograms
Weight: Kilograms
Loading Dose:
mL Acetadote OR mg Acetadote in
mL of diluent, infused over 60 minutes

Second Dose:
mL Acetadote OR mg Acetadote in
mL of diluent, infused over 4 hours

Third Dose:
mL Acetadote OR mg Acetadote in
mL of diluent, infused over 16 hours

The total volume administered should be adjusted for patients less than 40 kg (88 lbs) and for those requiring fluid restriction. To avoid fluid overload, the volume of diluent should be reduced as needed.

Diluent: Acetadote is compatible with 5% Dextrose (D5W), ½ Normal Saline, and Water for Injection.

NOTE: Stability studies indicate that the diluted solution is stable for 24 hours at controlled room temperature.

View full Prescribing Information including pediatric dosing


INDICATION

Acetadote is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of acetaminophen in patients with an acute ingestion or from repeated supratherapeutic ingestion.

IMPORTANT SAFETY INFORMATION
CONTRAINDICATIONS

Acetadote is contraindicated in patients with a previous hypersensitivity reaction to acetylcysteine.